USMLE USMLE : United States Medical Licensing Examination

  • Exam Code: USMLE
  • Exam Name: United States Medical Licensing Examination
  • Updated: Sep 17, 2026
  • Q & A: 400 Questions and Answers

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USMLE USMLE Exam Syllabus Topics:

TopicDetails
Topic 1
  • Infectious and inflammatory disorders of the eye
  • Adverse effects of drugs on the immune system
Topic 2
  • Adaptive behavioral responses to stress and illness
  • Biochemistry and molecular biology
Topic 3
  • Deficiency of phagocytic cells and natural killer cells
  • Adverse effects of drugs on the nervous system
Topic 4
  • Adverse effects of drugs on the hematologic and lymphoreticular systems
  • Disorders associated with immunodeficiency
Topic 5
  • Deficiency primarily of humoral immunity
  • Immunologic and inflammatory disorders
Topic 6
  • Cranial and peripheral nerve disorders
  • Cellular basis of the immune response and immunologic mediators

Reference: http://www.usmle.org/step-1/#question-formats

Step 1 of the USMLE (United States Medical Licensing Examination) is the first part of the United States Medical Licensing Examination. It is open to medical school student and graduates to assess their ability to apply important concepts fundamental to the practice of medicine. While American medical students usually take USMLE Step 1 at the end of the second year of medical school, all graduates of foreign medical schools must take this exam is they intend to practice medicine in the United States.

USMLE Step 2 is a one-day (8 hours) exam. Similar to the Step 1, the test items are divided into blocks, and test item formats vary within each block, with the total number of exam questions equaling to 355.

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